Generative Energy #22: A Bioenergetic View of Heart Disease and Stroke


“The heart’s unique behavior has given cardiologists a particularly mechanical perspective on biology. If a cardiologist and an oncologist have anything to talk about, it’s likely to be about why cancer treatments cause heart failure; a cardiologist and an endocrinologist might share an interest in “cardioprotective estrogen” and “cardiotoxic obesity.” Cell physiology and bioenergetics aren’t likely to be their common interest. Each specialty has its close involvement with the pharmaceutical industry, shaping its thinking. —Heart and hormones by Ray Peat ►

“Alterations in cardiac energy metabolism can profoundly affect cardiac efficiency. Excessive use of free fatty acids has been shown to be especially important, either by decreasing the efficiency of producing ATP, or by decreasing ATP availability for contractile function.” —Impact of fatty acid oxidation on cardiac efficiency ►

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01:18 - Rising interest in heart disease and stroke
05:45 - Heart disease begins at a very young age
07:27 - What’s the role of cholesterol in heart disease?
11:13 - The heart and hormones
17:55 - What’s the role of aldosterone “the salt-retaining hormone” in heart disease?
25:38 - Blood volume, sodium, and dietary protein
30:34 - The role of endotoxin in heart disease and stroke
33:09 - Aspirin for heart disease?
38:57 - “Normal” TSH and fatal coronary heart disease
40:20 - Is heart disease a mystery?
42:13 - Where can we find more of your work, Georgi?
42:57 - Do your own research and come to your own conclusions